Protocadherin, their antibodies and uses

Details Protocadherin, their antibodies and uses Protocadherin, their antibodies and uses

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 5/18 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2117581

Polynucleotide sequences encoding novel cadherin-like polypeptides, designated protocadherins, and variants thereof are provided by the invention as well as methods and materials for the recombinant production of the same. Antibody substances specific for protocadherins are also disclosed as useful for modulating the natural binding and/or regulatory activities of the protocadherins.

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