A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2528599
This invention relates to the newly identified utility of certain G protein- coupled receptors (GPCRs), in particular to OGR1, GPR4 and TDAG8 (TDAG8 is also named GPR65) polypeptides, and polynucleotides encoding such GPCR polypeptides, to their use in diagnosis and to methods of identifying compounds that are agonists or antagonists to said GPCRs, and to the production of such polypeptides and polynucleotides.
La présente invention concerne la nouvelle utilité récemment identifiée de certains récepteurs couplés à la protéine G (RCPG), notamment les polypeptides OGR1, GPR4 et TDAG8 (TDAG8 est également appelé GPR65) et les polynucléotides codant de tels polypeptides RCPG, leur utilisation pour le diagnostic et des méthodes d'identification de composés qui sont des agonistes ou des antagonistes des RCPG, ainsi que la production de tels polypeptides et polynucléotides.
Baumgarten Birgit
Jones Carol Elizabeth
Ludwig Marie-Gabrielle
Martiny-Baron Georg
Seuwen Klaus
Fetherstonhaugh & Co.
Novartis Ag
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