Prototype felv isolates for use in disease models and vaccines

Details Prototype felv isolates for use in disease models and vaccines Prototype felv isolates for use in disease models and vaccines

A - Human Necessities

61

K

167/130, 195/1.2

A61K 39/21 (2006.01) A61P 31/14 (2006.01) C07K 14/15 (2006.01) C12N 15/48 (2006.01) C12P 21/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2005311

Molecular clones of feline leukemia virus isolates that encode (a) a prototype highly infectious, minimally pathogenic virus, (b) a variant genome that is replication-defective and associated with a fatal immunodeficiency in cats similar to AIDS (FAIDS) or (c) a chimeric genome that is replication-competent and induces FAIDS. These molecular clones may be used to generate cell lines producing infectious virus which is useful in the preparation of vaccines or in the generation of viremia or disease challenge systems.

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