C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/30 (2006.01) A61K 39/002 (2006.01) C07K 14/44 (2006.01) C12N 1/10 (2006.01)
Patent
CA 2543866
The invention relates to a protozoan strain, belonging to theTrypanosomatidae family, whose virulence is lower than that of the corresponding wild strain, characterized in that at least one copy of the SIR2 gene, which is present in the genome of said strain, is inactivated.
La présente invention concerne une souche de protozoaire de la famille des Trypanosomatidae dont la virulence est inférieure à celle de la souche sauvage correspondante, caractérisée en ce qu~au moins une copie du gène SIR2 présente dans le génome de ladite souche est inactivée.
Cordeira Da Silva Anabela
Ouaissi Ali
Sereno Denis
Vergnes Baptiste
Goudreau Gage Dubuc
Institut de Recherche Pour Le Developpement
Universidade Do Porto
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