Prpsc -interacting molecules and uses thereof

Details Prpsc -interacting molecules and uses thereof Prpsc -interacting molecules and uses thereof

G - Physics

01

N

G01N 33/53 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) C07K 1/00 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2500120

Peptides are disclosed which specifically bind to PrPsc. Methods of identifying these peptides by sequence-independent and/or sequence-dependent screening assays are also disclosed. Various applications of the method and of the peptides identified are described, including their use for identifying drugs for treating prion diseases.

L'invention concerne des peptides se liant spécifiquement à PrP?sc¿. Elle concerne aussi des procédés d'identification de ces peptides par des tests de criblage indépendants et/ou dépendants des séquences. Elle concerne enfin différentes applications du procédé et des peptides identifiés, y compris leur utilisation pour identifier des médicaments destinés à traiter les maladies du prion.

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