Prrsv subunit vaccines

Details Prrsv subunit vaccines Prrsv subunit vaccines

A - Human Necessities

61

K

A61K 39/12 (2006.01) A61P 31/14 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2570778

Vaccines effective against PRRSV include at least one portion of PRRSV ORF1. Such vaccines, upon administration, provoke an immune response in PRRSV- susceptible animals. Moreover, compositions in accordance with the present invention provide immune response up to and including protective immunity against PRRSV as well as reduce the severity of PRRSV and/or incidence of PRRSV. Selected portions of ORF1 can be used singularly, in combination with one another, in combination with other PRRSV ORFs, and in combination with other PRRSV vaccines.

L'invention concerne des vaccins efficaces contre le virus du syndrome dysgénésique respiratoire porcin (PRRSV) qui comprennent au moins une partie du cadre de lecture ouvert (ORF1) du PRRSV. Une fois administrés, ces vaccins provoquent une réponse immunitaire chez des animaux sensibles au PRRSV. Par ailleurs, les compositions selon l'invention fournissent une réponse immunitaire englobant une immunité contre le PRRSV et réduisent la gravité du PRRSV et/ou l'incidence du PRRSV. Des parties sélectionnées de ORF1 peuvent être utilisées seules, combinées les unes aux autres, combinées à d'autres cadres de lecture ouverts (ORF) du PRRSV ou combinées à d'autres vaccins contre le PRRSV.

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