Psca: prostate stem cell antigen and uses thereof

Details Psca: prostate stem cell antigen and uses thereof Psca: prostate stem cell antigen and uses thereof

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2378946

The invention provides a novel prostate cell-surface antigen, designated Prostae Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.

L'invention porte sur un nouvel antigène de la surface de cellules souches prostatiques dit Prostate Stem Cell Antigen (PSCA), largement surexprimé à tous les stades du cancer de la prostate, dont la néoplasie prostatique intraépithéliale de haut degré (PIN), et les tumeurs prostatiques androgéno dépendantes ou non androgénodépendantes.

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