Pseudo-metalloproteins, corresponding preparation and use as...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 7/22 (2006.01) C07K 1/107 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C12Q 1/00 (2006.01) G01N 27/30 (2006.01) G01N 27/327 (2006.01) G01N 27/333 (2006.01) G01N 33/00 (2006.01)

Patent

CA 2419019

Described herein is a compound of general formula (I) in which: M is a metal selected among Fe, Mn, Ti, Mo, Co, Ni, Cu, Pd, Pt, Au, Ru, Cr, V, Tb, Yb, Rh, Ir, Os; X1 is an antigen, or else a functional group that enables association to a biomolecule; X2 is a functional group that enables association to an electrode; S1 and S2 are spacer groups made up of a chain of from 3 to 12 atoms of C, N, O, S and corresponding mixtures; all the other substituents have an amino acid nature. The said compound may be used to construct biosensors.

La présente invention concerne un composé de formule générale (I), dans laquelle: M est un métal choisi parmi Fe, Mn, Ti, Mo, Co, Ni, Cu, Pd, Pt, Au, Ru, Cr, V, Tb, Yb, Rh, Ir, Os ; X1 est un antigène, ou encore un groupe fonctionnel permettant une association avec une molécule; X2 est un groupe fonctionnel permettant une association avec une électrode; S1 et S2 des groupes de bras espaceurs constitués de chaînes de 3 à 12 atomes de C, N, O, S et les mélanges correspondants; tous les autres substituants sont de type acide aminé. Ledit composé peut être utilisé dans la production de biocapteurs.

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