Pseudopentapeptides with immunomodulating activity

Details Pseudopentapeptides with immunomodulating activity Pseudopentapeptides with immunomodulating activity

C - Chemistry, Metallurgy

07

K

C07K 7/02 (2006.01) A61K 38/04 (2006.01) C07K 5/02 (2006.01) C07K 14/66 (2006.01)

Patent

CA 2094822

2094822 9304080 PCTABS00020 Pseudopeptides of formula (.alpha.) wherein AA1 is an arginyl residue; AA2 is a basic amino acid residue, a neutral/nonaromatic amino acid residue or proline residue or is an N-alkylated (1-6C) form thereof; AA3 is an aspartic acid or glutamic acid wherein the remaining carboxyl group may be esterified with alkyl (1-6C), or an alanine residue; AA4 is a neutral/nonaromatic amino acid residue; AA5 is a neutral/aromatic amino acid residue wherein one or more hydrogens of its aromatic portion can be substituted by NO2 or halogen, or is a neutral/nonpolar/large/nonaromatic amino acid residue or the N-alkylated (1-6C) form thereof; R is acyl (1-6C), arylsulfonyl, alkylsulfonyl, arylalkylsulfonyl or alkoxycarbonyl group; and R1 is -OH, -NR2R3 or -OR4 wherein each of R2 and R3 is hydrogen or an alkyl group (1-6C) and R4 is alkyl group (1-6C); and wherein at least one of the linkages I-IV is a modified peptide linkage -COCH2-, -CH(OH)CH2- or -CH2NH-, and the remaining linkages are -CONH- or -CON(CH3)-.

Affiliated with

Also associated with

Rating

Pseudopentapeptides with immunomodulating activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pseudopentapeptides with immunomodulating activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pseudopentapeptides with immunomodulating activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1430273