C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/04 (2006.01) A61K 31/435 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2397593
The invention relates to a pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5, 7--dihydroxy-8-[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-one hydrochloride, a method of making the same, a pharmaceutical composition and its use for treating cancer and inhibiting protein kinases or cyclin dependant kinases in a patient.
L'invention concerne un pseudopolymorphe d'hydrochlorure (-)-cis-2-(2-chlorophényl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-méthyl)pipéridinyl]-4H-1-benzopyran-4-one, un procédé de fabrication correspondant, une composition pharmaceutique et des procédés relatifs à l'utilisation du pseudopolymorphe.
Bafus Gary L.
Harrison-Bowman Christine M.
Silvey Gary L.
Aventis Pharmaceuticals Inc.
Aventisub II Inc.
Robic
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