Pt(iv) complexes

Details Pt(iv) complexes Pt(iv) complexes

C - Chemistry, Metallurgy

07

F

167/119, 260/383

C07F 15/00 (2006.01) A61K 31/295 (2006.01) A61K 31/555 (2006.01)

Patent

CA 1340286

A Pt(IV) complex of the formula <see Fig.1> wherein A and A' are NH3 or an amino group; R and R1 are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally.

589796

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