C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/22 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C07H 19/06 (2006.01)
Patent
CA 2343134
The invention provides pteridine nucleotides of formula (I) which are highly fluorescent and which can be used in the chemical synthesis of fluorescent oligonucleotide. The invention further provides for fluorescent oligonucleotide comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures. The pteridine nucleotides are more stable and possess higher quantum yields than structurally similar pteridine nucleotides.
L'invention concerne des nucléotides de ptéridine de la formule (I), très fluorescents, qui peuvent être utilisés dans la synthèse chimique d'oligonucléotides fluorescents. L'invention concerne également des oligonucléotides fluorescents comprenant un ou plusieurs nucléotides de ptéridine. Elle concerne en outre des triphosphates de nucléotide de ptéridine pouvant être utilisés comme monomères constitutifs dans des procédés d'amplification de l'ADN. Ces nucléotides de ptéridine sont plus stables et donnent des rendements quantiques plus élevés que ceux de nucléotides de ptéridine présentant une structure similaire.
Balis Frank
Hawkins Mary E.
Pfleiderer Wolfgang
Sim & Mcburney
The Government Of The United States Of America Represented By Th
LandOfFree
Pteridine nucleotide analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pteridine nucleotide analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pteridine nucleotide analogs will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1505156