Pufa polyketide synthase systems and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/52 (2006.01) A01H 1/00 (2006.01) A01H 5/00 (2006.01) A23C 9/00 (2006.01) A23C 9/152 (2006.01) A23L 1/30 (2006.01) C12N 15/82 (2006.01) C12P 7/62 (2006.01) C12P 7/64 (2006.01) C12Q 1/04 (2006.01)

Patent

CA 2444164

The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to methods of making and using such system for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.

L'invention concerne globalement des systèmes à polyketide synthase (PKS) acides gras polyinsaturés (AGPI) isolés ou dérivés d'organismes non bactériens, leurs homologues, des molécules d'acide nucléique isolées et des molécules d'acide nucléique recombinées codant des domaines biologiquement actifs de ce système à PKS AGPI, des procédés de fabrication et d'utilisation associés à ce système pour la production de molécules d'intérêt bioactives et de nouvelles méthodes d'identification de nouveaux microorganismes non bactériens et bactériens comprenant ce système à PKS AGPI.

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