Pulmonary delivery of inhibitors of phosphodiesterase type 5

Details Pulmonary delivery of inhibitors of phosphodiesterase type 5 Pulmonary delivery of inhibitors of phosphodiesterase type 5

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 9/14 (2006.01) A61K 9/72 (2006.01) A61K 31/4985 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2575684

Provided herein are compositions of 1) diketopiperazine salts PDE5 inhibitors and 2) DKP microparticles having a PDE5 inhibitors thereon, as well as methods for the pulmonary delivery of these compositions for the treatment of pulmonary hypertension and sexual dysfunction(s).

La présente invention concerne des compositions constituées 1) de sels de dicétopipérazine d'inhibiteurs de PDE5 et 2) de microparticules de DKP sur lesquelles se trouvent des inhibiteurs de PDE5. Cette invention concerne également des procédés pour administrer par voie pulmonaire ces compositions afin de traiter une hypertension pulmonaire et des dysfonctionnements sexuels.

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