Pulmonary surfactant formulations and methods for promoting...

A - Human Necessities – 61 – K

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A61K 38/16 (2006.01) A61K 31/66 (2006.01)

Patent

CA 2663795

Methods and compositions to enhance mucus clearance and to treat of pulmonary lung disorders such as cystic fibrosis are disclosed. The methods utilize pulmonary surfactants, alone or combined with hyperosmotic agents, administered to patients in an amount effective to enhance mucus clearance. The compositions comprise a pulmonary surfactant combined with an osmotically active agent.

La présente invention concerne des procédés et des compositions destinés à favoriser l'élimination du mucus et à soigner les troubles pulmonaires, tels que la fibrose kystique. Lesdits procédés utilisent des surfactants pulmonaires, seuls ou associés à des agents hyperosmotiques, administrés à des patients dans une quantité efficace pour améliorer l'élimination du mucus. Les compositions comprennent un surfactant pulmonaire associé à un agent actif osmotiquement.

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