Pulsed low frequency epr spectrometer and imager

G - Physics – 01 – R

Patent

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Details

G01R 33/60 (2006.01) G01N 27/74 (2006.01)

Patent

CA 2166068

An EPR imager and spectrometer include pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.

Spectromètre et dispositif d'imagerie RPE comprenant un système qui génère des impulsions à large bande dont la fréquence porteuse HF n'est pas fortement absorbée par les échantillons biologiques. Le système générateur d'impulsions comprend des convertisseurs à expansion et compression qui modulent en fréquence l'impulsion de fréquence porteuse et compriment l'impulsion modulée en fréquence pour former une impulsion d'excitation à large bande de haute énergie. Une machine de ce type pourrait constituer le fondement d'un disposif d'imagerie clinique capable de détecter avec une extrême sensibilité certaines espèces de radicaux libres chez des patients humains.

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