Punctal plug comprising a water-insoluble polymeric matrix

A - Human Necessities – 61 – K

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Details

A61K 9/00 (2006.01) A61F 9/00 (2006.01) A61L 24/06 (2006.01)

Patent

CA 2669642

Disclosed is a pharmaceutical composition comprising a water insoluble polymer matrix that comprises a bioerodable polyester polymer or a fatty acid based polyester polymer, or a mixture of both polymers, wherein the polymer matrix has a melting point of less than 60°C, and wherein the composition is liquid or paste at room temperature and is formulated to occlude a punctual channel in a subject and conforms to the shape of the canalicular or punctal channel.

L'invention concerne une composition pharmaceutique comprenant une matrice polymère insoluble dans l'eau renfermant un polymère de polyester bioérodable ou un polymère de polyester à base d'acide gras, ou un mélange de ces deux polymères, cette matrice polymère présentant un point de fusion inférieur à 60°C. Ladite composition, liquide ou pâteuse à température ambiante, est préparée en vue de l'occlusion d'un canal lacrymal chez un patient. En outre, elle épouse la forme du canalicule ou du canal lacrymal.

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