C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/22 (2006.01) C07K 1/16 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C07K 16/06 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2739568
The present invention provides a method of removing product-related inactive and/or partially active species, high molecular weight aggregates, as well as other process-related impurities from preparations of acidic proteins by using ceramic hydroxyapatite chromatography.
La présente invention concerne un procédé qui permet déliminer des espèces inactives et/ou partiellement actives associées à un produit, des agrégats de poids moléculaire élevé, ainsi que dautres impuretés associées au procédé, de préparations de protéines acides par l'utilisation d'une chromatographie sur hydroxyapatite en céramique.
Jennings Priscilla
Luo Yin
Sun Shujun
Torys Llp
Wyeth Llc
LandOfFree
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