Purification of biologically active human immune...

B - Operations – Transporting – 01 – D

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167/103.1, 195/1

B01D 15/08 (2006.01) C07K 14/57 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1248448

ABSTRACT There is provided a process for purification of human immune interferon (IFN- .gamma.) to homogeneity without appreciable loss of biological activity by the use of chromatography on controlled-pore glass, ultra- filtration and high performance cation exchange chromatography, resulting in essentially pure human interferon subtypes 21K and 26K, and there are provided said purified interferons and pharmaceutical compositions containing same.

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