Purification of crude ioversol using reverse osmosis

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 237/46 (2006.01) A61K 49/04 (2006.01) B01D 61/02 (2006.01) C07C 231/24 (2006.01)

Patent

CA 2124561

2124561 9310887 PCTABS00022 A process of using reverse osmosis membrane as an alternative or substitute method for the purification of a crude diagnostic agent. Crude ioversol can be purified by drawing ioversol in a process tank (12), and pumping it into a housing cartridge (16) containing a reverse osmosis membrane (18), which allows the passage of aqueous solution of low molecular weight impurities, and retain larger molecular weight molecules of ioversol which are returned to the process tank (12).

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