Purification of interferon

Details Purification of interferon Purification of interferon

C - Chemistry, Metallurgy

07

K

167/103.1, 530/1

C07K 14/565 (2006.01)

Patent

CA 1133898

TITLE PURIFICATION OF INTERFERON ABSTRACT OF THE DISCLOSURE Human interferons produced in the absence of added serum or sera can be purified to greater than 95% protein purity by adsorption on immobilized Cibacron Blue F3G-A and eluting the interferon adsorbed on the Cibacron Blue F3G-A with ethylene glycol in an aqueous buffer solution. The purified interferon in solution can be converted to interferon of uniform molecular weight by heating the interferon solution in the presence of an organic thiol compound.

362018

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