Purification of polysaccharide-protein conjugate vaccines by...

A - Human Necessities – 61 – K

Patent

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A61K 39/385 (2006.01) A61K 39/09 (2006.01) A61K 39/095 (2006.01) C07K 14/34 (2006.01)

Patent

CA 2358022

The present invention relates to the removal of unbound polysaccharides from conjugated polysaccharide-protein vaccines using the method of ultrafiltration whereby the diafiltration solution contains saturating levels of ammonium sulfate.

L'invention porte sur l'extraction de polysaccharides non liés à partir de vaccins conjugués de protéine-polysaccharide par le procédé d'ultrafiltration, la solution de diafiltration contenant des niveaux de sulfate d'ammonium saturants.

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