C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 1/18 (2006.01) C07K 14/475 (2006.01) C07K 14/48 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2113815
2113815 9302206 PCTABS00019 Methods are provided for the production and purification of recombinant ciliary neurotrophic factor. The purification of C-terminal truncated forms of ciliary neurotrophic factor are also described. Methods are provided for preventing and treating peripheral nerve damage. The method comprises administering to patients in need thereof a therapeutically effective amount of CNTF. A preferred method for producing CNTF is by recombinant DNA technology.
Bonam Duane M.
Collins Franklin D.
Freund Erwin
Mcdonald John R.
Russell Deborah
Smart & Biggar
Syntex-Synergen Neuroscience Joint Venture
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