Purification of recombinant interleukin-2

C - Chemistry – Metallurgy – 07 – K

Patent

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195/1.32

C07K 14/55 (2006.01) C07K 1/14 (2006.01) C12N 15/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340853

Method for the preparation of substantially homogeneous recombinant mature human IL-2 comprising separating the cell membrane components from a lysate of transformed microorganisms which have expressed and accumulated IL-2, extracting IL-2 from the cell membrane components and purifying chromatographyically the extract.

470498

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