C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 305/14 (2006.01)
Patent
CA 2519474
This invention is directed to a method for isolating and /or purifying one or more taxanes from materials comprising taxanes. In one embodiment, the method comprises the steps of: (a) treating a taxane containing material with an amino containing material attached to a solid matrix, such as a polyethyleneimine-bonded silica chromatographic resin; (b) eluting the desired taxane compound from the resin; and (c) recovering the eluted taxane compound.
L'invention concerne un procédé d'isolement et/ou de purification d'un ou de plusieurs taxanes à partir de substances contenant des taxanes. Dans un mode de réalisation, le procédé consiste à: (a) traiter une substance contenant des taxanes avec un matériau contenant un groupement amine fixé sur une matrice solide, telle qu'une résine chromatographique de silice liée par polyéthlylèneimine; (b) éluer le composé taxane recherché de la résine; et (c) récupérer le composé taxane élué.
Bucher Brian A.
Franke Roland R.
Gallagher Rex T.
Hand Barry J.
Howe Christopher D.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Natural Pharmaceuticals Inc.
Phyton Holdings Llc
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