C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/14 (2006.01) A23J 1/00 (2006.01) C07K 7/56 (2006.01)
Patent
CA 2419889
There is disclosed a process for purifying a natural product using a two- phase, multi-solvent system followed by vacuum concentration and back extraction. The method allows for the removal of impurities by controlling the polarity balance of a two-phase system by manipulating the proportions of the four solvents and subsequently the relative distribution of the product versus the impurities.
L'invention concerne un procédé de purification d'un produit naturel utilisant un système diphasique, multi-solvants suivie d'une concentration sous vide et d'une réextraction. Le procédé permet l'élimination d'impuretés en régulant l'équilibre de polarité d'un système diphasique par manipulation des proportions des quatre solvants et, par conséquent, la distribution relative du produit par rapport aux impuretés.
Chandler Martin A.
Goklen Kent E.
Lee Steven S.
Roush David J.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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