Purification processes of echinocandin-type compounds

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 7/56 (2006.01) A01N 43/90 (2006.01) A01P 3/00 (2006.01) A61K 38/12 (2006.01) C07K 1/14 (2006.01) C07K 7/54 (2006.01) C12P 21/04 (2006.01)

Patent

CA 2662923

The present invention provides a method of preparing and purifying echinocandin- type compounds, such as pneumocandin Bo, WF 11899 A, and echinocandin B. These compounds are fermentation products that are used to prepare semi-synthetic products such as the antifungal products Caspofungin, Mycafungin, and Anidulafungin.

La présente invention concerne un procédé de préparation et de purification de composés de type échinocandine tels que la pneumocandine Bo, le WF 11899 A et l'échinocandine B. Ces composés sont des produits de fermentation qui sont utilisés pour préparer des produits semi-synthétiques tels que les produits antifongiques caspofungine, mycafungine et anidulafungine.

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