Purified amphilic peptide compositions and uses thereof

Details Purified amphilic peptide compositions and uses thereof Purified amphilic peptide compositions and uses thereof

A - Human Necessities

61

K

A61K 47/42 (2006.01) A61K 38/10 (2006.01) A61P 17/02 (2006.01) C07K 1/06 (2006.01) C08L 89/00 (2006.01) C40B 40/10 (2006.01)

Patent

CA 2572964

A plurality of amphiphilic peptide chains having alternating hydrophilic and hydrophobic amino acids, wherein the peptide contains at least 8 amino acids, are complementary and structurally compatible, and self-assemble into a beta- sheet macroscopic scaffold wherein peptide at least about 75% of the chains have the same sequence.

L'invention concerne une pluralité de chaînes peptidiques amphiphiles comprenant des acides aminés hydrophiles et hydrophobes alternants, le peptide comprenant au moins 8 acides aminés, les chaînes peptidiques étant complémentaires et compatibles du point de vue de la structure et à auto-assemblage dans un échafaud macroscopique de feuillet bêta, au moins 75 % des chaînes peptidiques ayant la même séquence.

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