Purified and antigenically selective vaccines for domestic...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/245 (2006.01) A61K 39/385 (2006.01)

Patent

CA 1213828

ABSTRACT Purified antigenically selective vaccines for domestic animals are prepared from microorganism cultures containing the immunizing agent by first complexing the immunizing agent with micro-particles having bound IgG antibodies specific for the immunizing agent, separating the resulting complex, and preparing a vaccine directly therefrom containing the antigen-antibody complex. The micro-particles preferably have Protein A in their outer surfaces for binding to the specific antibodies. The complex-containing vaccines provide effective immunization. The method and the resulting vaccines are particularly useful in preparing viral and bacterial subunit vaccines.

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