Purified antibodies specifically directed against the...

A - Human Necessities – 61 – K

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A61K 39/40 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2079804

2079804 9115239 PCTABS00106 La présente invention concerne des anticorps purifiés spécifiquement dirigés contre les lipopolysaccharides (LPS) des bactéries gram négatif, caractérisés en ce qu'ils sont obtenus en une étape avec un facteur d'enrichissement supérieur à 500 et de préférence supérieur à 750 en réalisant une chromatographie d'immunoaffinité des anticorps anti-LPS présents dans des liquides biologiques, ladite chromatographie mettant en oeuvre la fixation desdits anticorps sur des antigènes LPS immobilisés sur un support. La présente invention se rapporte également aux compositions pharmaceutiques contenant lesdits anticorps.

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