Purified antigen from non-a, non-b hepatitis causing factor

Details Purified antigen from non-a, non-b hepatitis causing factor Purified antigen from non-a, non-b hepatitis causing factor

G - Physics

01

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167/130, 167/140

G01N 33/576 (2006.01) A61K 39/29 (2006.01) C12N 1/00 (2006.01)

Patent

CA 1264292

Purified Antigen From Non-A, Non-B Hepatitis Causing Factor Abstract An isolated, purified non-A, non-B hepatitis (NANBH) associated antigen having the properties (a) molecular weight of monomer 77,000 daltons on sodium dodecyl sulphate polyacrylamide gel, (b) monomer reactive with rhesus monkey immune serum, (c) glycoprotein containing about 2% carbohydrate comprising (i) predominantly mannose and (ii) approximately equal molar amounts of fucose and galactose, (d) an aromatic amino acid composition comprising molar ratios of phenylalanine, tyrosine, and trypotophan of about 3:3:1, respectively, and (e) immunogenicity is disclosed along with methods of preparing and using the antigen.

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