Purified c5a receptor from human polymorphonuclear leukocytes.

Details Purified c5a receptor from human polymorphonuclear leukocytes. Purified c5a receptor from human polymorphonuclear leukocytes.

C - Chemistry, Metallurgy

07

K

530/15.06

C07K 14/705 (2006.01)

Patent

CA 2006955

TITLE OF THE INVENTION PURIFIED C5a RECEPTOR FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES ABSTRACT OF THE DISCLOSURE A method is disclosed for isolating and purifying C5a receptor from human polymorphonuclear leukocytes. C5a is a complement-derived protein which is important as a mediator of inflammatory responses. C5a receptor may be used to screen create and quantify C5a antagonists useful as anti-inflammatory agents and immunoregulants and to generate monoclonal and polyclonal anti-C5a receptor antibodies useful as anti-inflammatory agents and immunoregulants.

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