Purified cytokine inhibitory factor

Details Purified cytokine inhibitory factor Purified cytokine inhibitory factor

A - Human Necessities

61

K

A61K 35/54 (2006.01)

Patent

CA 2474360

Disclosed is a composition comprising a substantially purified Cytokine Inhibitory Factor (CIF) having certain characteristics, including the ability to inhibit RNA transcription of the pro-inflammatory cytokines tumor necrosis factor alpha (TNF-.alpha.), interleukin 1-beta (IL-1.beta.), and interleukin-2 (IL-2). Also disclosed is a method for substantially purifying the Cytokine Inhibitory Factor and a method for modulating the immune system of an animal using such composition.

L'invention concerne une composition contenant un facteur inhibiteur des cytokines (CIF) sensiblement purifié possédant certaines caractéristiques, notamment la capacité d'inhiber la transcription ARN des cytokines pro-inflammatoires que sont le facteur de nécrose tumorale alpha (TNF-.alpha.), l'interleukine 1-bêta (IL-1.beta.) et l'interleukine 2 (IL-2). L'invention concerne en outre un procédé pour purifier sensiblement le facteur inhibiteur des cytokines, ainsi qu'un procédé pour moduler le système immunitaire d'un animal au moyen de cette composition.

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