Purified lasofoxifene and a method for purification of...

Details Purified lasofoxifene and a method for purification of... Purified lasofoxifene and a method for purification of...

C - Chemistry, Metallurgy

07

D

C07D 207/08 (2006.01)

Patent

CA 2479924

A method for removing impurities from racemic cis-6-phenyl-5-[4-(2- pyrrolidin- 1-ylethoxy) phenyl]-5, 6, 7, 8- tetrahydronaphthalen-2-ol and purified cis-6- phenyl-5--[4-(2- pyrrolidin-1-ylethoxy) phenyl]-5, 6, 7, 8- tetrahydronaphthalen-2-ol useful as an estrogen agonist/ antagonist.

L'invention concerne un procédé permettant d'éliminer des impuretés de cis-6-phényl-5-[4-(2-pyrrolidin-1-yléthoxy)phényl]-5,6,7,8-tétrahydronaphthalène-2-ol et de cis-6-phényl-5-[4-(2-pyrrolidin-1-yléthoxy)phényl]-5,6,7,8-tétrahydronaphthalène-2-ol purifié servant d'agoniste/antagoniste des oestrogènes.

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