Purified mammalian flt3 ligands and agonists and antagonists...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2163105

This invention provides mammalian Flt3 ligands and fragments thereof, nucleic acids encoding the same, recombinant vectors and host cells comprising such nucleic acids, and antibodies or binding fragments thereof which specifically bind to the ligands or fragments thereof, kits, and pharmaceutical compositions for modifying the biological activity of cells bearing Flt3 ligand receptors. Methods for making and using the foregoing materials are also provided by this invention.

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