Purified plasmodium and vaccine compositions

Details Purified plasmodium and vaccine compositions Purified plasmodium and vaccine compositions

A - Human Necessities

61

K

A61K 39/015 (2006.01) A61P 33/06 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2749262

Disclosed are substantially purified Plasmodium sporozoites and preparations of Plasmodium sporozoites substantially separated from attendant non-sporozoite material, where the preparations of Plasmodium sporozoites have increasing levels of purity. Vaccines and pharmaceutical compositions comprising purified Plasmodium sporozoites are likewise provided. Methods of purifying preparations of Plasmodium sporozoites are also provided.

La présente invention concerne des sporozoïtes de Plasmodium substantiellement purifiés et des préparations de sporozoïtes de Plasmodium substantiellement séparés des matériels non-sporozoïtes attenants, les préparations de sporozoïtes de Plasmodium présentant des niveaux de pureté croissants. La présente invention concerne également des vaccins et des compositions pharmaceutiques de sporozoïtes de Plasmodium purifiés. La présente invention concerne en outre des méthodes de purification de sporozoïtes de Plasmodium.

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