Purified proteins and process therefor

Details Purified proteins and process therefor Purified proteins and process therefor

C - Chemistry, Metallurgy

07

K

167/103.1, 530/1

C07K 1/20 (2006.01) C07K 14/56 (2006.01) C07K 14/665 (2006.01)

Patent

CA 1129409

EV 4100/12 Abstract A process for purifying proteins having molecular weights greater than 12,000, such as interferon, which process comprises passing an aqueous solution of said protein in an impure state through a buffer equilibra- ted column of a modified porous silica matrix under high performance liquid chromatography conditions and eluting said protein with an increasing or decreasing gradient of an aqueous water miscible solvent.

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