Purifying polyoxyethylated castor oils with activated...

A - Human Necessities – 61 – K

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A61K 31/23 (2006.01) A01N 37/06 (2006.01) A61K 31/045 (2006.01) A61K 31/337 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 33/44 (2006.01) A61K 47/10 (2006.01) A61K 47/44 (2006.01) C07C 51/43 (2006.01) C07C 59/00 (2006.01) C07C 59/265 (2006.01) C11B 3/10 (2006.01)

Patent

CA 2397848

Disclosed are polyoxyethylated castor oils produced by preparing a suspension of activated charcoal and a polyoxyethylated castor oil; and separating the activated charcoal from the polyoxyethylated castor oil. The process removes impurities such as colorants and alkali metal cations. Also disclosed are compositions containing the treated castor oil and an active agent such as a pharmaceutical agent. The formulations have prolonged storage stability.

L'invention concerne des huiles de castor polyoxyéthylées produites par préparation d'une suspension de charbon activé et d'une huile de castor polyoxyéthylée, et par séparation du charbon activé de l'huile de castor polyoxyéthylée. Le procédé enlève les impuretés, telles que des colorants et des cations de métal alcalin. L'invention concerne également des compositions contenant l'huile de castor traitée et un principe actif, tel qu'un principe actif pharmaceutique. Les formulations possèdent une stabilité de stockage prolongée.

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