Purine compounds and xanthine oxidase inhibitors

Details Purine compounds and xanthine oxidase inhibitors Purine compounds and xanthine oxidase inhibitors

C - Chemistry, Metallurgy

07

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C07D 473/00 (2006.01) A61K 31/505 (2006.01) C07D 473/18 (2006.01) C07D 473/32 (2006.01) C07D 473/34 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2213420

Purine or triazolopurine compounds represented by general formula (I) or (II), wherein R1 and R4 represent each hydrogen, halogeno, hydroxy, mercapto or amino; R2 represents alkyl or aryl; and R3 and R5 represent each hydrogen, alkyl or aryl; and medicinal compositions comprising these compounds as the active ingredient in particular, xanthin oxidase inhibitors, remedies for hyperuricemia, or remedies or preventives for gout.

Composés de purine ou de triazolopurine représentés par la formule générale (I) ou (II), où R?1¿ et R?4¿ représentent chacun hydrogène, halogèno, hydroxy, mercapto ou amino; R?2¿ représente alkyle ou aryle; et R?3¿ et R?5¿ représentent chacun hydrogène, alkyle ou aryle; ainsi que les compositions médicinales comprenant ces composés comme substance active, et notamment des inhibiteurs de xanthine oxydase, des médicaments pour l'hyperuricémie ou des médicaments curatifs ou préventifs de la goutte.

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