Purine derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 19/167 (2006.01) A61K 31/70 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2152341

A compound of formula (I), or a pharmaceutically salt thereof, wherein X is halogen, trifluoromethyl, cyano, C1-6-alkoxy, C1-6-alkylthio, C1-6-alkylamino or C1-6-dialkylamino; R1 and R4 are H or straight or branched C1-6-alkyl or trifluoromethyl or R1 and R4 together form a cycloakyl ring; Y is O, S, SO2, NH or N-alkyl; R5 is selected from optionally substituted heterocycles: R6 and R7 are hydrogen, benzoyl or C1-6-alkanoyl. The compounds have been found useful for treating central nervous system and cardiovascular ailments.

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