Purine derivatives and their use as modulators of toll-like...

Details Purine derivatives and their use as modulators of toll-like... Purine derivatives and their use as modulators of toll-like...

C - Chemistry, Metallurgy

07

D

C07D 473/18 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2691444

The present application includes purine compounds of Formula I or II: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional active agent. Said compounds are used as modulators of Toll -like receptor 7.

La présente invention porte sur des composés de purine représentés par la Formule I ou II : ou sur les sels, solvates et/ou esters pharmaceutiquement acceptables de ces composés, sur des compositions contenant de tels composés, sur des procédés thérapeutiques qui comprennent l'administration de tels composés, et sur des méthodes thérapeutiques qui comprennent l'administration de tels composés avec au moins un agent actif supplémentaire. Lesdits composés sont utilisés comme modulateurs du récepteur de type Toll-7.

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