Purine derivatives inhibitors of tyrosine protein kinase syk

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 473/16 (2006.01) A61K 31/52 (2006.01) C07D 473/18 (2006.01) C07D 473/24 (2006.01)

Patent

CA 2379560

Compounds of formula (I) in free or salt form, where X, R1, R2, R3 and R4 are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of inflammatory or obstructive airways disease.

L'invention concerne des composés de formule (I) sous forme libre ou sous forme de sel, X, R<1>, R<2>, R<3> et R<4> étant tels que définis dans le descriptif, ainsi que leur préparation et leur utilisation en tant que composés pharmaceutiques, notamment pour le traitement d'inflammations ou d'obstructions des voies respiratoires.

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