Purine inhibitors of phosphodiesterase (pde) 7

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 473/06 (2006.01) A61K 31/00 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/513 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 473/16 (2006.01) C07D 487/04 (2006.01) C07D 491/10 (2006.01) C07D 498/10 (2006.01)

Patent

CA 2450936

Purine phosphodiesterase 7 (PDE 7) inhibitors of the following formulas(Ia, Ib), wherein R1, R2, Z, Y and J are described herein, and analogs thereof are provided which are useful in treating T-cell mediated diseases.

L'invention concerne des inhibiteurs puriques de phosphodiesterase 7 (PDE 7) représentés par les formules suivantes (Ia, Ib), dans lesquelles R?1¿, R?2¿, Z, Y et J ont la signification indiquée dans la description, et des analogues desdits inhibiteurs qui sont utiles dans le traitement de maladies induites par les lymphocytes T.

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