C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/044 (2006.01) A61K 31/706 (2006.01) A61P 31/14 (2006.01) C07H 19/052 (2006.01) C07H 19/056 (2006.01)
Patent
CA 2533367
This invention is directed to a method for treating a host, especially a human, infected with hepatitis C, flavivirus and/or pestivirus, comprising administering to that host an effective amount of an anti-HCV biologically active pentofuranonucleoside where the pentofuranonucleoside base is an optionally substituted 2-azapurine. The optionally substituted pentofuranonucleoside, or a salt or prodrug thereof, may be administered alone or in combination with one or more optionally substituted pentofuranonucleosides or other anti-viral agents.
La présente invention concerne une méthode pour traiter un hôte, notamment un être humain, infecté avec l'hépatite C, le flavivirus et/ou le pestivirus, consistant à administrer à cet hôte une quantité efficace d'un pentofuranonucléoside anti-HCV biologiquement actif, la base pentofuranonucléoside étant une 2-azapurine éventuellement substituée. Ce pentofuranonucléoside éventuellement substitué, ou bien son sel ou son promédicament, peut être administré seul ou en association avec un ou plusieurs pentofuranonucléosides éventuellement substitués ou bien d'autres agents antiviraux.
Dukhan David
Gosselin Gilles
Leroy Frederic
Storer Richard
Centre National de La Recherche Scientifique
Idenix (cayman) Limited
Idenix Pharmaceuticals Inc.
L'universite Montpellier II
Mbm Intellectual Property Law Llp
LandOfFree
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