C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/220, 260/242
C07D 473/30 (2006.01) A61K 31/52 (2006.01) C07D 233/90 (2006.01)
Patent
CA 1303037
A B S T R A C T PURINONE DERIVATIVES AS BRONCHODILATORS, VASODILATORS AND ANTI-ALLERGIC AGENTS Compounds of the formula (1) : Image (1) and pharmaceutically acceptable salts thereof are described, wherein R1 is C1-6alkyl or C2-6alkenyl, and R2 is hydrogen or hydroxy. These compounds have vasodilator, bronchodilator and anti-allergic properties. Pharmaceutical compositions are described as are methods of use. Processes for the preparation of the compounds of the formula (1) are described.
557327
Coates William J.
Gowling Lafleur Henderson Llp
Smith Kline & French Laboratories Limited
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