Purinone derivatives as bronchodilators vasodilators and...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/30 (2006.01) A61K 31/52 (2006.01) C07D 233/90 (2006.01)

Patent

CA 1303037

A B S T R A C T PURINONE DERIVATIVES AS BRONCHODILATORS, VASODILATORS AND ANTI-ALLERGIC AGENTS Compounds of the formula (1) : Image (1) and pharmaceutically acceptable salts thereof are described, wherein R1 is C1-6alkyl or C2-6alkenyl, and R2 is hydrogen or hydroxy. These compounds have vasodilator, bronchodilator and anti-allergic properties. Pharmaceutical compositions are described as are methods of use. Processes for the preparation of the compounds of the formula (1) are described.

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