Purinyl and pyrimidinyl tetrahydrofurans

Details Purinyl and pyrimidinyl tetrahydrofurans Purinyl and pyrimidinyl tetrahydrofurans

C - Chemistry, Metallurgy

07

H

260/229.1, 260/2

C07H 19/04 (2006.01) C07D 307/20 (2006.01) C07D 405/04 (2006.01) C07D 473/00 (2006.01) C07H 7/04 (2006.01)

Patent

CA 2012851

Antiviral activity is exhibited by compounds having the formula (see formula I) and pharmaceutically acceptable salts thereof wherein R1 is a purine or pyrimidine base or an analog thereof and R2 and R3 are independently hydrogen, -PO3H2 or (see formula II) wherein X7 is hydrogen, alkyl, substituted alkyl and aryl.

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