C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2362943
The present invention relates to novel Pyk2 binding proteins Pap alpha and Pap beta, nucleotide sequences encoding the novel Pyk2 binding proteins, as well as various products and methods useful for the diagnosis and treatment of various Pyk2 binding protein-related and protein kinase-related diseases and conditions. Through the use of a bioinformatics strategy, two mammalian members of the Pyk2 binding protein family have been identified and their protein structure predicted.
La présente invention concerne de nouvelles protéines fixatrices Pyk2, des séquences nucléotidiques codant pour ces nouvelles protéines, ainsi que divers produits et méthodes utilisés dans le diagnostic et le traitement de diverses maladies et divers états pathologiques liés à la protéine fixatrice Pyk2 et à la protéine kinase. Grâce à l'utilisation de systèmes bio-informatiques, deux membres mammaliens de la famille de la protéine fixatrice Pyk2 ont été identifiés et leur structure protéique déterminée.
Andreev Julian
Schlessinger Joseph
New York University
Smart & Biggar
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