C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/12 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2274805
The present invention features a method for treatment of an organism having a disease or condition characterized by an abnormality in a signal transduction pathway, wherein the signal transduction pathway includes a PYK2 protein. The invention also features methods for diagnosing such diseases and for screening for agents that will be useful in treating such diseases. The invention also features purified and/or isolated nucleic acid encoding a PYK2 protein.
La présente invention concerne une thérapie utilisable pour un organisme souffrant d'une affection ou d'une pathologie se caractérisant par une anomalie de voie de transduction du signal qui inclut une protéine PYK2. L'invention concerne également des techniques de diagnostic de telles affections et des techniques de recherche d'agents convenant au traitement de ces affections. L'invention concerne enfin un acide nucléique purifié et/ou isolé codant une protéine PYK2.
Lev Sima
Schlessinger Joseph
New York University Medical Center
Smart & Biggar
Sugen Inc.
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