Pyranobenzoxadiazole derivatives

C - Chemistry – Metallurgy – 07 – D

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167/231, 167/235

C07D 498/04 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01)

Patent

CA 1331990

ABSTRACT OF THE DISCLOSURE A compounds of the formula Image (I) wherein A represents OH or OC(O)CH3-nXn, B represents hydrogen atom, or A and B together represent a bond; R1 represents hydrogen atom, R2 represents hydrogen atom, C(Z)CH3-nXn or C(Z)NHCH3-nXn or R1 and R2 together represents ( CH2)m, (CH2)m-1C(Z), N(R3)(CH2)2C(Z), (CH2)m-2NHC(Z) or CH2)m-2OC(Z) in which X represents fluorine atom, chlorine atom, bromine atom, a methyl group or a methoxy group and n represents 0 or an integer of 1 to 3, Z represents oxygen atom or sulfur atom, m represents an integer of 4 or 5 and R3 represents hydrogen atom or a methyl group, and pharmacological acceptable salts of the compounds which can form salts, processes therefor and pharmaceutical use of the compounds.

590141

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