Pyranone compounds useful to treat retroviral infections

Details Pyranone compounds useful to treat retroviral infections Pyranone compounds useful to treat retroviral infections

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) C07D 311/02 (2006.01) C07D 311/20 (2006.01)

Patent

CA 2560489

The present invention relates to compounds of formulae (I) and (II) (see formula I) (see formula II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4- hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R10 and R20 taken together are formulae (III) and (IV). (see formula III) (see formula IV)

La présente invention concerne des composés de la formule (I) et (II) qui sont des pyran-2-ones, des 5,6-dihydropyran-2-ones, des 4-hydroxy-benzopyran-2-ones, des 4- hydroxycycloalkyl¬b|pyran-2-ones, ainsi que leurs dérivés. Ces composés sont utiles pour inhiber un rétrovirus dans une cellule de mammifère infectée par ledit rétrovirus. Dans les formules, R10 et R20 pris ensemble ont les formules (III) et (IV).

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